The antibacterial component from Cinnamomi Cortex against a cariogenic bacteriumStreptococcus mutans OMZ 176 |
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Authors: | Ki-Hwan Bae Jong-Myung Ji Kyung-Lae Park |
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Institution: | 1. College of Pharmacy, Chungnam Nat'l University, 305-764, Taejon, Korea
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Abstract: | The methanol extract of Cinnamomi Cortex showed antibacterial action against cariogenic bacterium,Streptococcus mutans OMZ 176. The active principle of the extract was identified to betrans-cinnamaldehyde, which was bactericidal in the minimal inhibitory concentration (MIC) of 100 μg/ml againt the strain. From the results of antibacterial activity of cinnamaldehyde and its derivatives, the acrolein group in the cinnamal-dehyde was elucidated to be an essential element for the activity. |
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