肺结核合并肝硬化26例临床分析

目的探讨肺结核合并肝硬化患者的抗结核治疗。方法回顾分析我院住院肺结核病人合并肝硬化26例,按肝硬化情况分为两组：代偿期组及失代偿期组,代偿期组予HRTEL,失代偿期组予HEL＋阿莫西林克拉维酸钾,两组患者在抗结核治疗同时均予积极护肝治疗及免疫治疗,严密监测肝功,乙肝肝硬化HBV-DNA阳性者予抗病毒治疗。结果26例化疗总好转率92.3%,仅有1例化疗半年后死亡。结论提示这类病人若能选择合适的抗结核方案,肺结核可收到良好治疗效果。

Clinical study of 26 patients with pulmonary tuberculosis complicated with liver cirrhosis

Objective To discuss the anti-tuberculosis therapeutic effect on patients with pulmonary tuberculosis complicated with liver cirrhosis.Methods 26 patients with pulmonary tuberculosis complicated with liver cirrhosis were studied.The patients were divided into two groups according to the condition of liver cirrhosis: the compensation phase group and the un-compensation phase group.The former group was treated with HRTEL,and the latter was treated with HEL+ amoxicillin potassium clavulanate.At the same time,the two groups were given the protective-liver treatment and immunity treatment, monitoring liver function exactly,and the liver cirrhosis HBV-DNA positive patients were given the anti-virus treatment.Results Twenty-Five of 26 cases were recovered,only 1 case died after treatment for half a year. Conclusion: Choosing suitable treatment program,the anti-tuberculosis treatment of patients with pulmonary tuberculosis complicated with liver cirrhosis can be effective.