| 果酸在皮肤科的应用 |
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| 引用本文： | 赵珏敏,项蕾红. 果酸在皮肤科的应用[J]. 中国麻风皮肤病杂志, 2016, 32(8): 500-504 |
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| 作者姓名： | 赵珏敏 项蕾红 |
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| 作者单位： | 复旦大学附属华山医院皮肤科，上海，200040 |
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| 摘 要： | 果酸是一种天然无毒的酸，可以降低角质形成细胞的黏着性，加速表皮细胞脱落与更新，同时刺激真皮胶原合成、黏多糖增加及弹力纤维的修复，对抗光老化，改善皮肤干燥，修复屏障功能，已被广泛应用于美容护肤领域。本文就果酸的历史发展、化学种类、作用机制、临床应用、不良反应进行综述。
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| 关 键 词： | 果酸 痤疮 黄褐斑 光老化 |
Application of glycolic acid in dermatology |
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| ZHAO Juemin,XIANG Leihong. Application of glycolic acid in dermatology[J]. China Journal of Leprosy and Skin Diseases, 2016, 32(8): 500-504 |
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| Authors: | ZHAO Juemin XIANG Leihong |
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| Affiliation: | Department of Dermatology, Huashan Hospital Affliated to Fudan University, Shanghai 200040, China |
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| Abstract: | Glycolic acid is one organic hydroxyacid which can diminish cohesion of keratinocyte, accelerate desquamation and renewal of the stratum corneum, as well as increase the synthesis of collagen, elastic fiber and glycosaminoglycans. Glycolic acids also play a role in the prevention of photoaging, improvement of dry skin condition and repair of skin barrier function, which has been used widely in dermatology. The history of glycolic, species, mechanisms of action, clinical application and adverse reaction were reviewed in this pa￣per. |
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| Keywords: | glycolic acids acne melasma photoaging |
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