生物反馈放松疗法治疗高血压病人的焦虑障碍

目的 观察生物反馈放松疗法治疗原发性高血压病人焦虑障碍的临床疗效.方法 对60例原发性高血压伴焦虑障碍的病人,在抗高血压药（氨氯地平）常规治疗的基础上,研究组30例加用生物反馈系统联合放松训练治疗,对照组30例加用抗焦虑药物舍曲林（sertraline）治疗.使用汉密尔顿焦虑量表（Hamilton anxiety scale,HAMA）、匹兹堡睡眠质量指数（Pittsburgh sleep quality index,PSQI）、副反应量表及测量诊所血压、评定临床疗效,于治疗前及治疗6周末各评定1次.结果 治疗后两组的HAMA、PSQI总分均显著低于治疗前（P＜0.01）,但研究组治疗后的HAMA、PSQI总分比对照组有显著性降低（P＜0.05和P＜0.01）;研究组治疗后的诊所测量的收缩压和舒张压低于对照组（P＜0.01）而不良反应少于对照组.结论 生物反馈放松疗法可治疗原发性高血压病人的焦虑障碍,并可明显改善睡眠总体水平、增强抗高血压药的疗效,是高血压病人伴焦虑障碍的一种安全有效的治疗.

Effects of biofeedback relaxation therapy for anxious disorder in patients with essential hypertension

Objectives To study on clinical effects of the treatment for anxious disorder by biofeedback relaxation therapy in patients with essential hypertension. Methods Sixty cases of middle-old aged patients with essential hypertension were randomly divided into biofeedback group (30 cases) and control group (30 cases). The biofeedback group underwent with biofeedback relaxation therapy for 6 weeks, at the same time of receiving oral anti-hypertension drug(amlodipine). The control group patients took oral anti-anxiety drug(sertraline) and anti-hypertension drug(amlodipine). The clinical effects were assessed by Hamilton Anxiety Scale (HAMA-14), Pittsburgh Sleep Quality Index (PSQI), side-effects scale (SERS), systolic blood pressure (SBP) and diastolic blood pressure (DBP) before and after 6 week treatment. Results The scores of HAMA and PSQI in both two group were significantly lower than pre-treatment(P<0.01), but the scores of HAMA and PSQI in biofeedback group was more obviously decrease than the control group after treatment(P<0.05 and P<0.01). The blood pressure (SBP and DBP) of biofeedback group were significantly lower than control group after treatment(P<0.01). And the biofeedback group had less side-effect than control group. Conclusions Biofeedback relaxation therapy could reduce anxiety in the patients with essential hypertension and improve their sleep quality, as well as increase the effect of anti-hypertension drug. The therapy is a safe and effective for anxious disorder patient with essential hypertension.