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三种不同投硒方法防治儿童大骨节病效果观察
引用本文:吴振甲 罗福贤. 三种不同投硒方法防治儿童大骨节病效果观察[J]. 地方病通报, 1991, 6(2): 97-99
作者姓名:吴振甲 罗福贤
作者单位:甘肃省平凉地区地方病防治研究所(吴振甲,罗福贤),甘肃省平凉地区地方病防治研究所(白生琦)
摘    要:本文报告了采用三种不同投硒方法防治儿童大骨节病的结果。经过三年的防治实验表明,在食用1/6万硒盐的同时加服适量硒片效果最佳,控制了干骺端新发和进展。单服硒片效果次之。这两种防治方法使干骺端阳性率和病情活跃指数逐年下降。单食硒盐效果最差。与空白对照点相比有效率差异性不显著,患病人数,干骺端阳性率及病情活跃指数逐年升高,且趋向活跃。 三年防治结果表明硒对干骺端改变(早期)有肯定的治疗效果,对其他部位也有不同程度的修复效果,但明显低于干骺端的疗效,硒对预防儿童大骨节病新发效果欠佳。

关 键 词:大骨节病 硒 儿童 X线诊断

An Observation on the Therapeutic Effects of Selenium on Kaschin-Beck Disease in Children
Wu Zhen-jia,et al. An Observation on the Therapeutic Effects of Selenium on Kaschin-Beck Disease in Children[J]. Endemic Diseases Bulletin, 1991, 6(2): 97-99
Authors:Wu Zhen-jia  et al
Abstract:Children with Kaschin-Beck disease were divided into 3 groups and given selenate pills (Group A), 1/60000 seleniferous salt combined with selenate pills (Group B) and seleniferous salt alone (Goup C), respectively, to observe the therapeutic effects of selenium by different oral administrations in a 3-year trial. Results showed that therapeutic effects of Group B was the best, which could stop metaphyseal changes or prevent them from worsening and Group A was better than Group C. Group C showed no significant effect compared with the control group. The observation suggested that selenium was somewhat effective in Kaschin-Beck disease control, especially in preventing metaphyseal changes from worsening, but it was not effective enough to prevent children from Kaschin-Beck disease affection.
Keywords:Kaschin-Beck disease  Selenium  Therapy  Children  X-ray diagnosis
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