| 婴幼儿肺炎IL-2R和细胞体液免疫功能的检测 |
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| 引用本文： | 谢体泉,申丽婷. 婴幼儿肺炎IL-2R和细胞体液免疫功能的检测[J]. 山东医药, 2002, 42(8): 18-19 |
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| 作者姓名： | 谢体泉 申丽婷 |
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| 作者单位： | 成武县人民医院,山东成武,274200 |
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| 摘 要： | 对 32例轻症和 44例重症婴幼儿肺炎检测外周血中可溶性白细胞介素 2受体 (s IL- 2 R)、白细胞介素 2膜受体 (m IL- 2 R)、T淋巴细胞亚群、血清 Ig、Ig A、Ig M和补体 C3的变化。结果 :重症婴幼儿肺炎 s IL- 2 R显著高于轻症婴幼儿肺炎 ,轻症高于对照组 (P<0 .0 5 ) ,而 m IL- 2 R则重症低于轻症、轻症低于对照组 (P<0 .0 5 ) ;婴幼儿肺炎 T细胞亚群 CD8显著低于对照组 (P<0 .0 5 ) ,CD4/ CD8高于对照组 (P<0 .0 5 ) ;Ig G、Ig A、Ig M和补体 C3重症低于轻症、轻症低于对照组 (P<0 .0 5 )。结果提示 s I1- 2 R和 m I1- 2 R表达异常和细胞免疫紊乱及体液免疫不足是婴幼儿肺炎的易患因素 ,且与病情严重程度有相关性。
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| 关 键 词： | 白细胞介素2受体 淋巴细胞亚群 免疫球蛋白 肺炎 婴幼儿 |
| 修稿时间： | 2001-12-10 |
Interlerkinz receptor and lymphocyte subsets were tested in infants with pneumonia |
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| Xie Tichuan,Shen Liting. Interlerkinz receptor and lymphocyte subsets were tested in infants with pneumonia[J]. Shandong Medical Journal, 2002, 42(8): 18-19 |
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| Authors: | Xie Tichuan Shen Liting |
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| Abstract: | To study the susceptability of infants with pneumonia(IP),sIL-2R,mIL-2R,T-lymphocyte subsets and immunue protein were tested in 76 case of IP.The results showed that sIL-2R were significantly higher and mIL-2R were lower in IP than that in control(P<0.05).CD_8,IgG,IgA,IgM and complement Cs3 were obviously lower,CD_4/CD_8 higher in IP than control(P<90.05).These results suggested that the unnormalization of sIL-2R and mIL-2R expression,imblance of lymphocyte subsets ration and short of immune proteins are relate to infants with pneumonia. |
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| Keywords: | Interlerkin-2 receptor Lymphocyte subsets Immune Protein Pneumonia infant |
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