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| +Gz暴露对大鼠海马毛细血管超微结构的影响 | |
| 引用本文： | 徐冶,李质馨,田洪艳,陈默然,朱辛为,窦肇华,夏迎春.+Gz暴露对大鼠海马毛细血管超微结构的影响[J].吉林医药学院学报,2005,26(2):73-75. |
| 作者姓名： | 徐冶 李质馨 田洪艳 陈默然 朱辛为 窦肇华 夏迎春 |
| 作者单位： | 1. 吉林医药学院,组织胚胎学教研室,吉林,吉林,132013 2. 吉林医药学院,科研学术处,吉林,吉林,132013 3. 黑龙江省哈尔滨市军分区干休所卫生所,黑龙江,哈尔滨,150010 |
| 摘 要： | 目的探讨+Gz重复暴露对大鼠海马毛细血管超微结构的影响。方法SD大鼠60只,随机分成对照组、+Gz重复暴露后1h、6h、12h、24h和48h组,每组10只。采用动物离心机,建立+Gz引发急性脑缺血模型;常规透射电镜标本制备;对+Gz暴露后不同时间大鼠海马毛细血管超微结构进行观察。结果海马毛细血管超微结构于+Gz重复暴露后1h开始改变,12h改变最重,48h基本恢复正常。结论+Gz重复暴露导致脑缺血,引起毛细血管超微结构的可逆性损伤。 |
| 关 键 词： | 正加速度 大鼠 海马 毛细血管 |
| 文章编号： | 1009-8488(2005)02-0073-02 |
| 修稿时间： | 2005年5月10日 |
Effect of +Gz exposures on rat's hippocampus capillary |
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| XU Ye,LI Zhi-xin,TIAN Hong-Yan,CHEN Mo-ran,Zhu Xin-wei,DOU Zhao-Hua,XIA Ying-chun.Effect of +Gz exposures on rat''s hippocampus capillary[J].Journal of Jilin Medical College,2005,26(2):73-75. | |
| Authors: | XU Ye LI Zhi-xin TIAN Hong-Yan CHEN Mo-ran Zhu Xin-wei DOU Zhao-Hua XIA Ying-chun |
| Abstract: | Objective This research observed ultra structure changes of hippocampus capillary after +Gz exposures.Methods Sixty conscious SD rats served as the subjects. They were randomly divided into six groups. By means of an animal centrifuge, we set up a model of acute brain ischemia resulting from +Gz exposures, and use electron microscope to observe the structure of hippocampus capillary at different time after repeated +Gz exposures. Results We found that the ultra structure of capillary started to change at 1 h after +Gz exposures, and it changed most distinctly at 12 h. The structure recovered to normal at 48 h.Conclusion This study demonstrates there is brain ischemia after +Gz exposures, and it induce structure changes of hippocampus capillary, a reversible injury. |
| Keywords: | positive acceleration rat hippocampus capillary |
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