冠心病患者糖调节异常情况研究

目的 了解在天津医科大学总医院心内科住院的冠心病患者糖调节异常的患病情况。方法 自2005年6月1日至8月31日,天津医科大学总医院心内科连续入组符合冠心病诊断标准的住院患者67例。除此前已明确诊断糖尿病的冠心病患者外,其余均接受口服葡萄糖耐量试验（OGTT）检测,以了解糖调节状况。结果 冠心病患者合并糖调节异常率高达88.1%,其中糖尿病的患病率达56.7%,糖调节受损的患病率达31.3%。如果不进行OGTT检测,42.5%合并糖调节异常的患者将不能被诊断出糖尿病,48.0%的糖调节受损患者将被漏诊,85.0%的患者将不能被发现存在糖调节异常状态。结论 天津医科大学总医院心内科冠心病患者大多合并糖调节异常,需进行OGTT检测对其糖调节状态做出及时、准确的诊断。

Prevalence Survey on the Status of Abnormal Glucose Regulation in Patients with Coronary Artery Disease

Objective To investigate the prevalence of abnormal glucose regulation （AGR） in patients with coronary artery disease （CAD） in the department of cardiology of Tianjin Medical University General Hospital. Methods Sixty seven patients with CAD in the department of cardiology of Tianjin Medical University General Hospital were consecutively recruited from Jun 1, 2005 to Aug 31, 2005, Patients were asked to perform oral glucose tolerance test （OGTT） to characterize the glucose regulation status except for those with previously known diabetes mellitus （DM）. Results Most of patients with CAD in the study had abnormal glucose regulation. The prevalence of AGR was 88.1%. The prevalence of DM and IGT were 56.7% and 31.3%, respectively. Without OGTr, 42.5% DM and 48% IGR and 85% AGR would remain undiagnosed by fasting plasma glucose （FPG） detection alone. Conclusion A majority of patients with CAD in the study have AGR and OGTT is needed to promptly and accurately disclose these patients.