| 消化道肿瘤组织芯片中BAG-1的表达及意义分析 |
| |
| 引用本文： | 林雨冬,师建国,闫庆国,王明元,王星.消化道肿瘤组织芯片中BAG-1的表达及意义分析[J].中国康复理论与实践,2006,12(3):222-223,F0003. |
| |
| 作者姓名： | 林雨冬 师建国 闫庆国 王明元 王星 |
| |
| 作者单位： | 1. 第四军医大学西京医院病理科,陕西,西安市,710032
2. 南京军区福州总医院95临床部,福建,莆田市,351100 |
| |
| 摘 要： | 目的 检测抗凋亡基因BAG-1在多种消化道肿瘤中的表达，并讨论其意义。方法 利用组织芯片，采用免疫组化DAKO Envision法检测食道癌、胃癌、直肠癌及正常组织中BAG-1的表达。结果 食道癌、胃癌及直肠癌组织中BAG-1的表达比其对应的正常组织为高（P〈0．01）。结论 BAG-1在消化道肿瘤组织中表达高于正常组织，提示BAG-1表达可能与消化道恶性肿瘤的发生有关。
|
| 关 键 词： | 免疫组织化学 消化道肿瘤 组织芯片 |
| 文章编号： | 1006-9771（2006）03-0222-02 |
| 收稿时间： | 2006-01-10 |
| 修稿时间： | 2006年1月10日 |
Expression and Significance of Apoptosis Related Gene BAG-1 in Digestive Tract Cancer by Tissue Microarray |
| |
| LIN Yu-dong, SHI Jian guo, YAN Qing-guo,et al..Expression and Significance of Apoptosis Related Gene BAG-1 in Digestive Tract Cancer by Tissue Microarray[J].Chinese Journal of Rehabilitation Theory and Practice,2006,12(3):222-223,F0003. |
| |
| Authors: | LIN Yu-dong SHI Jian guo YAN Qing-guo |
| |
| Institution: | LIN Yu-dong, SHI Jian guo, YAN Qing-guo, et al. |
| |
| Abstract: | ObjectiveTo detect BAG1 expressions in digestive tract cancer by tissue microarray and to evaluate its clinical significance.MethodsTissue microarray of digestive tract cancer and normal tissues were analyzed by DAKO Envision system immunohistochemical staining for apoptosis related gene BAG-1 expression.ResultsThe positive rate of BAG-1 expression among esophagus cancer,gastric cancer and rectal cancer were higher than that of normal tissues respectively(P<0.01).ConclusionThere is an overexpression of BAG-1 in digestive tract cancer,which suggest that apoptosis related gene BAG-1 may be related to these cancer. |
| |
| Keywords: | BAG-1 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
