International Union of Pharmacology. LX. Retinoic acid receptors |
| |
| Authors: | Germain Pierre Chambon Pierre Eichele Gregor Evans Ronald M Lazar Mitchell A Leid Mark De Lera Angel R Lotan Reuben Mangelsdorf David J Gronemeyer Hinrich |
| |
| Institution: | Centre National de la Recherche Scientifique/Institut National de la Santé et de la Recherche Médicale/Université Louis Pasteur, Illkirch, Communauté Urbaine de Strasbourg, France. germain@titus.u-strasbg.fr |
| |
| Abstract: | Retinoid is a term for compounds that bind to and activate retinoic acid receptors (RARalpha, RARbeta, and RARgamma), members of the nuclear hormone receptor superfamily. The most important endogenous retinoid is all-trans-retinoic acid. Retinoids regulate a wide variety of essential biological processes, such as vertebrate embryonic morphogenesis and organogenesis, cell growth arrest, differentiation and apoptosis, and homeostasis, as well as their disorders. This review summarizes the considerable amount of knowledge generated on these receptors. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
