|
|||||
|
|
A multinational observational investigation of illness perceptions and quality of life among patients with a Fontan circulation |
|
| Authors: | Christina E. Holbein PhD Nicholas D. Fogleman MS Kevin Hommel PhD Silke Apers PhD Jessica Rassart MSc Philip Moons PhD RN Koen Luyckx PhD Maayke A. Sluman MD Junko Enomoto PhD Bengt Johansson MD PhD Hsiao‐Ling Yang PhD RN Mikael Dellborg MD PhD Raghavan Subramanyan MD Jamie L. Jackson PhD Werner Budts MD PhD Adrienne H. Kovacs PhD Stacey Morrison PsyD Martha Tomlin Cnp Kathy Gosney Mssw Alexandra Soufi MD Katrine Eriksen MSc Corina Thomet MSc Malin Berghammer PhD Luis Alday MD Edward Callus PhD Susan M Fernandes PA‐C Maryanne Caruana MD Samuel Menahem MD Stephen C. Cook MD Gwen R. Rempel PhD RN Kamila White PhD Paul Khairy MD PhD Shelby Kutty MD Gruschen Veldtman MBChB Frcp APPROACH‐IS consortium the International Society for Adult Congenital Heart Disease |
| Affiliation: | 1. Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA;2. University of Louisville, Louisville, Kentucky, USA;3. KU Leuven, Leuven, Belgium;4. University of Gothenburg, Gothenburg, Sweden;5. Amsterdam Medical Center, Amsterdam, The Netherlands;6. Chiba Cardiovascular Center, Chiba, Japan;7. Ume? University, Ume?, Sweden;8. National Taiwan University, Taipei, Taiwan;9. Adult Congenital Heart Unit, Sahlgrenska University Hospital, Gothenburg, Sweden;10. Frontier Lifeline Hospital, Dr. K. M. Cherian Heart Foundation, Chennai, India;11. Nationwide Children's Hospital, Columbus, Ohio, USA;12. University Hospitals Leuven and Department of Cardiovascular Sciences, Leuven, Belgium;13. Oregon Health & Science University, Portland, Oregon, USA;14. Hospital Louis Pradel, Lyon, France;15. Oslo University Hospital, Oslo, Norway;16. University Hospital Bern, University of Bern, Bern, Switzerland;17. University West, Trollh?ttan, Sweden;18. Hospital de Ni?os, Córdoba, Argentina;19. IRCCS Policlinico San Donato Hospital, Milan, Italy;20. Stanford University, Palo Alto, California, USA;21. Mater Dei Hospital, Msida, Malta;22. Monash Medical Center, Melbourne, Australia;23. Helen DeVos Children's Hospital, Grand Rapids, Michigan, USA;24. University of Alberta, Edmonton, Canada;25. Washington University and Barnes Jewish Heart & Vascular Center, University of Missouri, Saint Louis, Missouri, USA;26. Montreal Heart Institute, Montreal, Canada;27. Children's Hospital & Medical Center, Omaha, Nebraska, USA |
| Abstract: | Objective: First, to compare QOL and illness perceptions between patients with a Fontan circulation and patients with anatomically simple defects (ie, atrial septal defects [ASD] or ventricularseptal defects [VSD]). Second, to explore illness perceptions as a mediator of the associationbetween congenital heart disease (CHD) diagnosis and QOL. Design: Cross-sectional observational study. Setting: Twenty-four cardiology centers from 15 countries across five continents. Patients: Four hundred thirty-five adult patients with congenital heart disease (177 Fontan and258 ASD/VSD) ages 18-83 years. Outcome Measures: QOL and illness perceptions were assessed by the Satisfaction With LifeScale and the Brief Illness Perceptions Questionnaire, respectively. Results: Patients with a Fontan circulation reported lower QOL (Wald Z = -3.59, p 5 <.001) andmore negative perceptions of their CHD (Wald Z = -7.66, p < .001) compared with patients withASD/VSD. After controlling for demographics, anxiety, depressive symptoms, and New York HeartAssociation functional class, path analyses revealed a significant mediation model, αβ = 0.15,p = .002, 95% CI = 0.06-0.25, such that CHD diagnosis was indirectly related to QOL through illness perceptions. Conclusions: The Fontan sample’s more negative perceptions of CHD were likely a reflection oflife with a more complex defect. Illness perceptions appear to account for unique differences inQOL between groups of varying CHD complexity. Psychosocial screening and interventions may beimportant treatment components for patients with CHD, particularly those with Fontan circulations. |
| Keywords: | congenital heart disease Fontan circulation illness perceptions quality of life |
| 点击此处可从《Congenital heart disease》浏览原始摘要信息 | |
| 点击此处可从《Congenital heart disease》下载免费的PDF全文 | |