首页 | 本学科首页   官方微博 | 高级检索  
     

大剂量肝素超声雾化吸入辅助治疗哮喘急性发作49例的临床评价
引用本文:范崇伦,徐冬梅. 大剂量肝素超声雾化吸入辅助治疗哮喘急性发作49例的临床评价[J]. 滨州医学院学报, 2003, 26(5): 352-353
作者姓名:范崇伦  徐冬梅
作者单位:1. 济南市中心医院内科,济南市,250013
2. 济南市第三人民医院内科
摘    要:目的:探讨大剂量肝素超声雾化吸入辅助治疗哮喘急性发作的疗效。方法:49例慢性支气管哮喘急性发作期的住院病人随机分成两组:大剂量肝素超声雾化吸入组28例;小剂量肝素超声雾化吸入组21例。分别于20ml。盐水中加入12.5万单位及1.25万单位肝素超声雾化吸入。结果:与小剂量肝素组比较,大剂量肝素组及两组治疗前后患者最大呼气流速(PEFR),1秒用力呼气量(FEVl)和1秒用力呼气量与用力肺活量的比值(FEV1%)明显改善,具有板显著性差异,而患者血凝指标无明显变化。结论:大剂量肝素雾化吸入可明显改善患者的肺功能。

关 键 词:支气管哮喘 雾化吸入 肝素 大剂量 辅助治疗
文章编号:1001-9510(2003)05-0352-02
修稿时间:2003-04-26

EVALUATION OF THE THERAPEUTIC EFFECTS OF LARGE DOSES OF HEPARIN INHALED IN THE AEROSOL FORMATION FOR THE TREATMENT OF ACUTE EPISODE OF SEVERE ASTHMA
Fan Chonglun,Xu Dongmei. EVALUATION OF THE THERAPEUTIC EFFECTS OF LARGE DOSES OF HEPARIN INHALED IN THE AEROSOL FORMATION FOR THE TREATMENT OF ACUTE EPISODE OF SEVERE ASTHMA[J]. Journal of Binzhou Medical College, 2003, 26(5): 352-353
Authors:Fan Chonglun  Xu Dongmei
Abstract:Objective:In order to determine the therapeutic effects of large doses of heparin inhaled in the aerosol formation for the treatment of acute episode of severe asthma.Methods:Forty nine patients with acute episode of bronchial asthma were randomly divided into two groups .Large and small doses of groups of 28 and 21 cases were nebulized with 125 000 and 12 500 U of heparin dissolved in 20 mL saline respectively.Results:PEFR,FEV 1 and FEF% in the large doses group were markedly improved compared with those in the small doses group statistically,while the platelets,APTT and PT remained unchanged.Conclusion:Large doses of heparin can markedly improve pulmonary function with no apparent side effects.
Keywords:bronchial asthma  nebulized inhalation  heparin
本文献已被 CNKI 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号