参薏汤治疗慢性萎缩性胃炎45例临床观察

目的 :观察参薏汤对慢性萎缩性胃炎及癌前病变的作用。方法 :将75例慢性萎缩性胃炎患者随机分为两组 ,治疗组45例给予参薏汤 ,对照组30例给予硫糖铝、吗叮啉治疗 ,疗程均为6个月。观察两组患者临床、病理疗效 ,治疗前后萎缩、肠化、异型增生等变化。结果 :治疗组临床总有效率为91 % ,对萎缩、肠化、异型增生的有效率分别为64 %、67 %、65% ,与对照组比较有显著性差异(P<0.05)。结论 :参薏汤对慢性萎缩性胃炎及癌前病变有改善作用 ,且无明显毒副作用。

Clinical Observation of Shenyi Decoction on 45 Patients with Chronic Atrophic Gastritis

Objection: To observe the effect of Shenyi decoction in treating chronic atrophic gastritis and precancerous lesion. Methods: 75 patients with chronic atrophic gastritis were randomly divided into two groups, 45 cases in treatment group treated with Shenyi decoction and 30 cases in control group with ulcerlmin and domperidone, both for six months. The clinical and pathological curative effects and the changes of atrophy, intestinal metaplasia and heterohyperplastic before and after treatment were detected. Result: In the treatment group, the total effective rates were 91%, and the effective rates in atrophy, intestinal metapalasia and heterohyperplastic were 64%,67%and 65%respectively, which had a significantly differences with that of the control group(P<0.05). Conclusion: Shenyi decoction has an improvement in treating chronic gastritis and precancerous lesion, even hasn't obviously toxic and side effect.