经导管动脉内灌注尿激酶治疗急性脑动脉阻塞

目的 :探讨动脉血管内溶栓治疗急性脑动脉阻塞的疗效和价值。方法 :在DSA机下采用超选择性动脉插管灌注尿激酶治疗 48例急性脑动脉闭塞疾患。平均发病时间 2 9.6h ,尿激酶用量 80 0 0 0～ 3 0 0 0 0 0IU ,灌注时间持续 45～48min。结果 :6例患者即刻完全再通 ,3 8例部分再通 ,4例未通 ,临床有效率为 91.6%。结论 :超选择性动脉内灌注尿激酶是治疗急性脑动脉闭塞性疾病的优先选择方法。

Application of transcatheter intraarterial infusion of urokinase for acute cerebral arterial occlusion

Objective:To evaluate the efficiency of intraarterial infusion ofurokinase for acute cerebral arterial occlusion.Methods:Superselective intraarterial infusion of UK was performed in 48 patients suffered acute cerebral arterial occlusion at DSA unit.The mean time from the onset of the illness to the beginning of infusion was 29.6 hours.The dosage of UK was 80000～300000IU，and the duration of infusion 45～48 minutes.Results:Immediate complete recanalization was achieved in 6 patients,partial recanalization in 38 patients and remaining occlusion in 4 patients .The response rate was 91.6%.Conclusion:Superselective intraarterial infusion of UK is a preferential procedure of choice for acute cerebral arterial occlusion.