Single-breath induction of anesthesia: comparison of enflurane and sevoflurane |
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Authors: | Masaki Yurino Hitomi Kimura |
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Institution: | (1) Department of Anesthesiology and Resuscitology, Asahikawa Medical College, 4-5-3-11, Nishikagura, 078 Asahikawa, Hokkaido, Japan |
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Abstract: | In this study induction of anesthesia using the single-breath technique with either enflurane or sevoflurane in oxygen was
compared. Each group consisted of 16 unpremedicated volunteers who breathed approximately 1.7 minimum alveolar concentration
(MAC) equivalents of either vapor. There were no significant differences in the cardiovascular and respiratory variables monitored.
The induction of anesthesia with enflurane (141±41 s) required significantly more time than with sevoflurane (118±25 s). The
enflurane group was associated with significantly more problems during induction, and showed moderate or sometimes severe
excitatory movements of the extremities and/or coughing. Subjects in the enflurane group described the induction of anesthesia
as less pleasant than in the sevoflurane group. We concluded that enflurane was less suitable for single-breath induction
of anesthesia compared with sevoflurane. |
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Keywords: | Enflurane Sevoflurane Single-breath induction |
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