Mitotic Langerhans cell as a possible sign of activation in ichthyosis |
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Authors: | Lasse Kanerva Kirsti-Maria Niemi |
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Affiliation: | Section of Dermatology, Institute of Occupational Health, Helsinki University Hospital, Helsinki (2), Finland.;Department of Dermatology, Helsinki University Hospital, Helsinki (2), Finland. |
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Abstract: | The fine structure of Lagerhans cells (LC) in four rare types of ichthyosis, namely recessive ichthyosis congenita type II, III and IV and ichthyosis hystrix Curth-Macklin was examined. Signs of LC activation were observed in eight of 21 patients. In IC type IV, the rare occurrence of a mitotic LC was observed. It is possible that LCs are secondarily activated in keratinization disorders. |
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