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Thin-layer isoelectric focusing of hemoglobin variants: Screening and determination of isoelectric points |
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| Authors: | A. Giuliani M. Marinucci M.P. Cappabianca D. Maffi L. Tentori |
| Affiliation: | Laboratorio di Patologia non Infettiva, Instituto Superiore di Sanità, RomeItaly |
| Abstract: | The high resolving power of thin-layer isoelectric focusing was applied for screening some hemoglobin variants classified on the basis of their electrophoretic mobility in: electrophoretically slow variants (as Hb A2), electrophoretically slow variants (as Hb S), electrophoretically fast variants (Hbs type J).An analysis of the variant compounds has been performed, and the corresponding pI values were determined in whole hemolysate. |
| Keywords: | Correspondence should be addressed to: Professor L. Tentori Laboratorio di Patologia non Infettiva Instituto Superiore de Sanità viale Regina Elena 299-00161 Roma Italy. |
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