The absolute configuration of urinary 2-hydroxybutyric acid in patients with ketosis and lactic acidosis |
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Authors: | J.P. Kamerling G.J. Gerwig M. Duran D. Ketting S.K. Wadman |
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Affiliation: | 1. University Children''s Hospital “Het Wilhelmina Kinderziekenhuis”, Nieuwe Gracht 137, Utrecht The Netherlands;2. Laboratory of Organic Chemistry, University of Utrecht, Croesestraat 79, Utrecht The Netherlands |
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Abstract: | The absolute configurations of urinary 2-hydroxybutyrate and 3-hydroxybutyrate were determined in patients with lactic acidemia and ketosis by capillary gas-liquid chromatography of their O-acetylated (?)-menthyl ester derivatives. 2-Hydroxybutyrate had the L-configuration, whereas 3-hydroxybutyrate was in the d-configuration. |
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Keywords: | To whom correspondence should be addressed. |
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