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The absolute configuration of urinary 2-hydroxybutyric acid in patients with ketosis and lactic acidosis
Authors:J.P. Kamerling  G.J. Gerwig  M. Duran  D. Ketting  S.K. Wadman
Affiliation:1. University Children''s Hospital “Het Wilhelmina Kinderziekenhuis”, Nieuwe Gracht 137, Utrecht The Netherlands;2. Laboratory of Organic Chemistry, University of Utrecht, Croesestraat 79, Utrecht The Netherlands
Abstract:The absolute configurations of urinary 2-hydroxybutyrate and 3-hydroxybutyrate were determined in patients with lactic acidemia and ketosis by capillary gas-liquid chromatography of their O-acetylated (?)-menthyl ester derivatives. 2-Hydroxybutyrate had the L-configuration, whereas 3-hydroxybutyrate was in the d-configuration.
Keywords:To whom correspondence should be addressed.
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