| 核苷类药物单独和联合治疗慢性乙型肝炎的现状 |
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| 引用本文： | 孙洪运,谌翠容,潘红英. 核苷类药物单独和联合治疗慢性乙型肝炎的现状[J]. 国际流行病学传染病学杂志, 2010, 37(1). DOI: 10.3760/cma.j.issn.1673-4149.2010.01.019 |
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| 作者姓名： | 孙洪运 谌翠容 潘红英 |
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| 作者单位： | 1. 浙江中医药大学第一临床医学院,杭州,310053
2. 浙江中医药大学附属第六医院内四科,杭州,310014 |
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| 摘 要： | 抗病毒疗法是治疗慢性乙型肝炎的关键.核苷类药物单独或者联合抗病毒,对HBeAg阳性或是阴性的慢性乙型肝炎患者均显示有病毒学、生化学和组织学的益处,但在长期应用中产生不同的抗药性,限制了其临床应用.此文就核苷类药物单独和联合治疗慢性乙型肝炎的现状进行概述.
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| 关 键 词： | 肝炎,乙型,慢性 核苷类药物 现状 |
Current status of chronic hepatitis B treatment with nucleoside/nucleotide analogues by mootherapy and combination therapy |
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| SUN Hong-yun,CHEN Cui-rong,PAN Hong-ying. Current status of chronic hepatitis B treatment with nucleoside/nucleotide analogues by mootherapy and combination therapy[J]. International Journal of Epidemiology and Infectious Disease, 2010, 37(1). DOI: 10.3760/cma.j.issn.1673-4149.2010.01.019 |
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| Authors: | SUN Hong-yun CHEN Cui-rong PAN Hong-ying |
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| Abstract: | Antiviral therapy is regarded as the key of chronic hepatitis B treatment. In terms of virology, biochemics and histology, no matter nucleoside/nucleotide analogues are used in monotherapy or combination therapy, these medicines can benefit all the patients, whose HBeAg are positive or negative. However, the drug-resistance occurs frequently in the long-term application, limiting its clinic effects. This thesis aims to give general introduction of the current status of chronic hepatitis B treatment with nucleoside/nucleotide analogues by monotherapy and combination therapy. |
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| Keywords: | Hepatitis B,chronic Nucleoside/nucleotide analogues Present situation |
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