TOP输液泵在VAD方案治疗多发性骨髓瘤中的应用及护理

目的: 探讨输液泵持续输入化疗药物治疗多发性骨髓瘤(MM)的临床应用价值及护理要点。方法: 23例确诊为MM患者,随机分为治疗组11例,应用输液泵泵入化疗药物;对照组12例,使用常规输液方法,两组均采用VAD方案(硫酸长春地辛、盐酸吡柔比星和地塞米松)。结果: 治疗组共进行26个疗程化疗,对照组29个疗程化疗,治疗组静脉炎、皮肤损伤、口腔溃疡、恶心呕吐及便秘发生率均低于对照组(P<0.05~P<0.01)。结论: 采用输液泵给药具有恒速、恒量、单位时间内用药量稳定、副作用小的特点,TOP输液泵应用于MM的VAD化疗是一种安全、简便、省时省力的好方法。

Application and nursing of TOP transfusion pump in the VAD projet for treating multiple myeloma

Objective: To study the clinical application value and nursing point of transfusion pump in chemotherapy for multiple myeloma. Methods: Twenty-three patients with multiple myeloma were final diagnosis, 11 patients were distributed into treatment group and others were control group randomly. Infusion pump was adopted in treatment group, while common transfusion was used to control group. All treatment projects were VAD. Results: Twenty-six and 29 courses of chemotherapy were undertaken in treatment group and control group respectively. The incidence rates of phlebophlogosis, skin destruction, nausea and vomiting, dental ulcer and costiveness in treatment group were lower than those in control group, the difference were significance (P<0.05-P<0.01). Conclusions: The method of administer drags has the characteristics of persistent rate and quanitity, dose stability in unit time and adver-se reaction little, it is good method for its safety credibility, simpleness efficianey and time-saving.