石家庄市2006-2008年健康人群麻疹抗体水平监测

目的了解健康人群麻疹免疫水平,为加速控制和消除麻疹提供科学依据。方法采用间接ELISA法检测石家庄市2006-2008年健康人群麻疹IgG抗体水平。结果麻疹IgG抗体总阳性率为86.32%,几何平均滴度(GMT)为1:1367.18;3年IgG抗体阳性率差异无统计学意义(x2=2.71,P=0.258),GMT差异有统计学意义(F=3.330,P=0.036);不同年龄组麻疹抗体阳性率和GMT差异均有统计学意义(x2=37.539,P=0.000,F=2.849,P=0.009)。结论我市局部有些地方仍有低接种率和免疫空白,建议两剂次麻疹疫苗(MV)常规免疫后应在中小学入学前各强化接种一次MV。

Surveillance of Measles Antibody Level among The Healthy Population of Shijiazhuang during 2006 to 2008

Objective To understand the immunity level to measles among the healthy population and provide scientific evidence for control and eliminating measles.Method IgG antibody for measles in the healthy population of Shijiazhuang from 2006～2008 were tested by indirect ELISA.Results The positive rate and GMT were 86.32% and 1：1367.18 separately;There was no difference among positive rates in the three years （x^2=2.71,P=0.258）,while there was difference in GMT（F=3.330,P=0.036）;There were differences in positive rates and GMT among different age groups（x^2=37.539,P=0.000,F=2.849,P=0.009）.Conclusions There were still low coverage area and non-immune area,therefore it was recommended that supplemental immunization of MV was needed before entrance of junior school after two doses routine vaccination.