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血府逐瘀汤对肺栓塞患者D-二聚体和肺泡动脉血氧分压差的影响
引用本文:马靖华,;刘宁,;屈玲,;郝海宁,;赵景杰.血府逐瘀汤对肺栓塞患者D-二聚体和肺泡动脉血氧分压差的影响[J].河南中医药学刊,2014(10):1413-1415.
作者姓名:马靖华  ;刘宁  ;屈玲  ;郝海宁  ;赵景杰
作者单位:[1]榆林市第一医院,陕西榆林718000; [2]延安大学第一附属医院,陕西延安716000; [3]西安交通大学第二附属医院,陕西西安710003
基金项目:陕西省自然科学基金项目(编号:2013002)
摘    要:目的:探讨血府逐瘀汤对肺栓塞患者D-二聚体和肺泡动脉血氧分压差P(A-a)O2]的影响。方法:肺栓塞患者80例随机分为观察组40例,给予血府逐瘀汤治疗;对照组40例,给予对症支持处理。比较两组患者治疗后D-二聚体和P(A-a)O2水平变化情况,并分析不同D-二聚体水平和不同P(A-a)O2水平发生肺栓塞情况。结果:治疗后观察组D-二聚体、P(A-a)O2显著低于对照组(P〈0.05);D-二聚体〉500μg·L^-1者发生肺栓塞的几率显著高于D-二聚体〈500μg·L^-1者(P〈0.05);P(A-a)O2〉50 mmHg者发生肺栓塞的几率显著高于P(A-a)O2〈50 mmHg者(P〈0.05)。结论:血府逐瘀汤能有效改善患者肺泡血氧合状态,D-二聚体联合P(A-a)O2诊断肺栓塞能提高诊断率,尤其是对于D-二聚体超过500μg·L^-1,同时P(A-a)O2高于50 mmHg者,要提高临床重视,早期诊断肺栓塞。

关 键 词:肺栓塞  血府逐瘀汤  D-二聚体  肺泡血动脉氧分压差

Influence of Xuefuzhuyu Soup on D-dimer and Alveolar-Arterial Oxygen Pressure Difference of Patients with Pulmonary Embolism
Institution:Ma Jinghua,Liu Ning,Qu Ling,Hao Haining,Zhao Jingjie( 1. The First Hospital of Yulin, Yulin Shaanxi China 718000 ;2. The First Affiliated Hospital of Yan'an University, Yanan Shaanxi China 716000; 3. The Second Affiliated Hospital of Xi'an Jiao Tong University,Xi'an Shaanxi China 710003)
Abstract:Objective: To investigate the influence of Xuefuzhuyu Soup on D-dimer and alveolar-arterial oxygen pressure differenceP( Aa) O2]of patients with pulmonary embolism. Methods:80 cases with pulmonary embolism were divided into two groups,40 cases with the observation group were used Xuefuzhuyu Soup treatment,the control group with 40 patients were used symptomatic and supportive treatment,then D-dimer and PA-aO2 levels were compared in the two groups and different D-dimer levels and different levels of PA-aO2 with pulmonary embolism were analyzed. Results: After treatment,D-dimer levels and P( A-a) O2 levels of the observation group were significantly lower than that of the control group( P〈0. 05); Ratio of pulmonary embolism of patients with D-dimer 500 μg·L^-1was higher than that of D-dimer 500 μg·L^-1( P〈0. 05); Ratio of pulmonary embolism of patients with P( A-a) O2 50 mmHg ratio was higher than P( A-a) O2 50 mmHg( P〈0. 05). Conclusion: Xuefuzhuyu Soup can effectively improve blood oxygenation status and re-duce alveolar hypercoagulable,P( A-a) O2 combined with D-dimer can better improve the diagnosis of pulmonary embolism diagnosis,especially for P( A-a) O2 than 50 mmHg while D-dimer exceed 500 μg·L^-1,and they should improve the clinical importance of early diagnosis of pulmonary embolism.
Keywords:pulmonary embolism  xuefuzhuyu soup  D-Dimer  blood alveolar-arterial oxygen difference
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