| 原发性高血压患者血清ficolin-3、免疫球蛋白、补体及CRP水平研究 |
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| 引用本文： | 李桂新,刘士平,徐裕海,武云龙,曹华军.原发性高血压患者血清ficolin-3、免疫球蛋白、补体及CRP水平研究[J].大连医科大学学报,2016,38(4):367-370. |
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| 作者姓名： | 李桂新 刘士平 徐裕海 武云龙 曹华军 |
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| 作者单位： | 1. 大连医科大学附属第一医院 检验科,辽宁大连,116011;2. 大连医科大学附属第一医院体检中心,辽宁大连,116011 |
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| 摘 要： | 目的 分析原发性高血压患者血清纤维胶凝蛋白3(ficolin-3)、免疫球蛋白、补体及CRP水平与原发性高血压的关系.方法 选取大连医科大学附属第一医院高血压患者98例(其中单纯高血压88例,合并2型糖尿病10例),同时选取血压正常并无其他疾病的同期健康体检者42例作为对照组.采用ELISA法测定两组血清ficolin-3水平,采用散射比浊法测定两组血清补体(C3、C4)、免疫球蛋白(IgA、IgG、IgM)及CRP水平.比较各组各指标的变化.结果 高血压组ficolin-3、C3、C4水平均高于对照组(均P＜0.01),CRP水平高于对照组(P＜0.05),IgM水平低于对照组(P＜0.05),IgG和IgA水平与对照组比较未见显著性差异(P＞0.05).ficolin-3、C3、C4和CRP水平与血压呈正相关(P＜0.05);ficolin-3与C3、C4水平呈正相关,与高血压病程也呈正相关(均P＜0.05).结论血清ficolin-3水平与原发性高血压病的发展有关,对原发性高血压发病机制的研究、病情观察和预后有一定的价值.
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| 关 键 词： | 原发性高血压 补体 免疫球蛋白 ficolin-3 CRP |
| 收稿时间： | 2016/5/17 0:00:00 |
Analysis of ficolin-3, immunoglobulin, complement and CRP in patients with essential hypertension |
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| LI Gui-xin,LIU Shi-ping,XU Yu-hai,WU Yun-long and CAO Hua-jun.Analysis of ficolin-3, immunoglobulin, complement and CRP in patients with essential hypertension[J].Journal of Dalian Medical University,2016,38(4):367-370. |
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| Authors: | LI Gui-xin LIU Shi-ping XU Yu-hai WU Yun-long and CAO Hua-jun |
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| Institution: | Department of Clinical Laboratory, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China;,Physical Examination Center, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China,Department of Clinical Laboratory, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China,Department of Clinical Laboratory, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China; and Department of Clinical Laboratory, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China; |
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| Abstract: | |
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| Keywords: | essential hypertension complement immunoglobulin ficolin-3 CRP |
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