子宫颈冷刀锥切术诊治子宫颈上皮内瘤变61例临床分析

目的探讨宫颈冷刀锥切术（CKC）在宫颈上皮内瘤变（CIN）诊治中的价值。方法对2010年1月至2011年10月在北京大学人民医院妇科门诊经阴道镜下活检病理确诊为CIN2／3并行CKC的61例患者的临床资料进行回顾性分析。结果CKC术后与术前阴道镜活检病理级别的符合率为78．7％（48／61），其中16．4％（10／61）升级，4．9％（3／61）降级。发现宫颈浸润癌8例，切缘阳性2例。结论CKC是一种诊断治疗宫颈上皮内瘤变的简单、安全的方法，可以提高CIN2／3诊断准确率，有助于宫颈浸润癌的早期诊断。

Analysis of 61 cases of cervical intraepithelial neoplasia treated by cold knife conization

Objective To investigate the value of cervical cold knife conization （CKC） for the diagnosis and treatment of cervical intraepithelial neoplasia （CIN）. Methods Data of 61 CIN patients who underwent cervical CKC in Peking University People% Hospital from January 2010 to October 2011 were analyzed retrospectively. Re- suits Compared to biopsybased diagnosis the identical increased and reduced rate of pathological grade was 48 （78.7%）, 10 （16.4%） and 3 （4. 9%） cases. 8 cases of cervical invasive carcinoma, 2 cases of cutedge positive were found. Conclusion CKC is a simple and safe method to diagnose and treat CIN, and it can increase the early diagnosis rate of invasive cervical cancer.