小儿急性血液透析临床分析

目的　 探讨血液透析在小儿急性肾功能衰竭及药物、毒物中毒中治疗的临床意义和影响疗效的因素。 方法 　对40例 10个月～ 14岁急性危重肾功能衰竭及药物、毒物中毒患儿 14 0例次血液透析进行分析。 结果 　痊愈、好转占 2 4例( 6 0 0 %) ,主要并发症为低钾血症 ( 6 1 9%)、失衡综合征 ( 13 6 %)、低血压 ( 10 0 %)和出血 ( 7 8%)。疾病转归与首次透析时尿素氮、肌酐无相关性。 结论 　血液透析是抢救小儿急性肾功能衰竭的安全有效的方法。疗效与原发病、治疗时机和并发症的严重程度有关。

A clinical analysis of acute hemodialysis in children

Objective To investigate the clinical significance and the factors influencing efficacies of hemodialysis (HD) in children's acute renal failure (ARF) and drug or poison intoxication.Methods 140 times of HD were carried out in 40 patients from 10 months to 14 years of ARF and drug or poison intoxication.Results 24 cases recovered completely and improved clinically.The major complications were hypokalemia (61^9%),imbalanced syndrome (13^6%),hypotension (10^0%) and hemorrhage (7^8%) respectively.No correlation of the outcome was found with the first blood level of BUN or Cr in HD.Conclusion HD is a safe and effective treatment for severe ARF.The efficacies are related to the primary disease,therapy opportunity and severity of complications.