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Computed tomography assessment of exogenous surfactant-induced lung reaeration in patients with acute lung injury |
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| Authors: | Qin Lu Mao Zhang Cassio Girardi Belaïd Bouhemad Jozef Kesecioglu Jean-Jacques Rouby |
| Affiliation: | 1.Multidisciplinary Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Assistance Publique-H?pitaux de Paris,La Pitié-Salpêtrière Hospital, UPMC Univ Paris 06,Paris,France;2.Department of Emergency Medicine, Second Affiliated Hospital,Zhejiang University, School of Medicine,Hangzhou,China;3.Department of Anesthesiology,Federal University of Sao Paulo, Escola Paulista de Medicina,S?o Paulo,Brazil;4.Department of Intensive Care Medicine,University Medical Center Utrecht,Utrecht,The Netherlands |
| Abstract: | IntroductionPrevious randomized trials failed to demonstrate a decrease in mortality of patients with acute lung injury treated by exogenous surfactant. The aim of this prospective randomized study was to evaluate the effects of exogenous porcine-derived surfactant on pulmonary reaeration and lung tissue in patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS). |
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