HPLC法测定活血舒脉胶囊中人参皂苷Rg_1、Rb_1及三七皂苷R_1的含量

目的考察活血舒脉胶囊中人参皂苷Rg1、Rb1及三七皂苷R1的含量,为制订活血舒脉胶囊质量标准提供科学的实验依据。方法采用HPLC法对10个批号的活血舒脉胶囊中人参皂苷Rg1、Rb1及三七皂苷R1进行含量测定。结果10批样品中人参皂苷Rg1、Rb1、三七皂苷R1最低含量分别为14.862、14.258、2.864mg.g-1;RSD分别为2.53%、1.12%、2.11%。结论10批样品测定结果表明各成分含量稳定,RSD均小于3.0%,可以作为制订活血舒脉胶囊质量标准的依据。

Determination of ginsenoside Rg1,Rb1 and notoginsenoside R1 in Huoxue Shumai Capsule by HPLC

OBJECTIVE Determination of ginsenoside Rg1,Rb1 and notoginsenoside R1 in Huoxue Shumai Capsule in order to offer scientific experiment evidence for drawing the quality standard of Huoxue Shumai Capsule.METHODS Measure the content of ginsenoside Rg1、Rb1 and notoginsenoside R1 in 10 groups of Huoxue Shumai Capsule by HPLC.RESULTS In the 10 groups of samples,the lowest content of ginsenoside Rg1,Rb1 and notoginsenoside R1 were 14.862,14.258,2.864mg·g-1 separately and RSD were 2.53%,1.12%,2.11%.CONCLUSION The results indicated that the content of the three ingredients in the 10 groups sample are steady and all RSD less than 3.0%.According to the results,we can draw the quality standard of Huoxue Shumai Capsule.