幽门螺旋杆菌阳性胃溃疡临床治疗研究

目的 探讨幽门螺旋杆菌（HP）阳性胃溃疡临床治疗效果.方法 以106例HP阳性胃溃疡患者为研究对象.将患者随机均分为观察组和对照组,每组各53例.观察组采取雷贝拉唑、克拉霉素、阿莫西林、硫糖铝治疗.对照组采取雷贝拉唑、克拉霉素、阿莫西林治疗.7d为1个疗程.治疗4个疗程后用胃镜观察患者溃疡愈合率、HP根除率和不良反应发生情况.结果 观察组治愈率（92.45％）高于对照组治愈率（26.42％）,差异具有统计学意义（P＜0.05）.观察组HP根除率（96.23％）高于对照组HP根除率（73.58％）,差异具有统计学意义（P＜0.05）.两组患者均无严重不良反应.结论 雷贝拉唑、克拉霉素、阿莫西林、硫糖铝联合治疗幽门螺旋杆菌阳性胃溃疡效果显著,值得临床推广.

Clinical Observation on Peptic Ulcer Correlated with Helicobacter Pylori

Objective To explore the clinical effect of peptic ulcer correlated with helicobacter pylori. Methods 106 cases of patients with positive gastric ulcer were randomly divided into two groups. The observation group were treated with rabeprazole ＋ clarithromycin ＋ amoxicillin ＋ sueralfate. The control group were treated with rabeprazole ＋ clarithromycin ＋ amoxicillin. 7d was a course. The concrescence rate of the ulcer, the HP eradication rate and adverse reaction were compared. Results The cure rate of the treatment group （92.45%） were much better than that of the control group（26.42% ） （P 〈0.05） ; The HP eradication rate of the treatment group（96. 23% ） were much better than that of the control group（ 73.58% ） （ P 〈 0.05 ）. There was no serious adverse reaction. Conclusion It is effective remarkable treatment for peptic ulcer correlated with helieobacter pylori by rabeprazole ＋ clarithromycin ＋ amoxicillin ＋ sucralfate, and it is worth of clinical use.