脑卒中患者医院获得性肺炎危险因素分析

目的 探讨脑卒中患者医院获得性肺炎的危险因素,并预防其发生.方法 选择2010-01 ～2012-12间在我院住院的892例脑卒中患者作为研究对象.调查脑卒中患者医院感染的发生状况及其可能影响因素,并检测其病原菌及抗生素敏感性.应用多因素Logistic回归分析探讨其影响因素.结果 所有892例脑卒中患者中,共发生医院获得性肺炎65例,发生率为7.29％.病原学检测结果显示,位居前4位的病原菌分别为鲍曼不动杆菌、肺炎克雷伯菌、铜绿假单孢菌及真菌白色念珠菌,抗生素敏感性多重耐药,泛耐药有增加趋势.多因素Logistic回归分析显示,年龄、住院时间、伴糖尿病、伴心力衰竭、H2受体阻滞剂和预用抗生素等因素具有统计学意义,是脑卒中并发医院获得性肺炎的独立危险因素.结论 脑卒中并发医院获得性肺炎受到多种因素的影响,在临床实践中应针对这些因素积极采取措施,以降低该病的发生率.

Risk Factors of Hospital Acquired Pneumonia in Stroke Patients

Objective To investigate risk factors of hospital - acquired pneumonia in stroke patients, aimed at preventing its occu- rrence. Methods 892 stroke patients treated from January 2010 to December 2012 in the hospital were enrolled as research subjects. In- vestigating the incidence of nosocomial infection and its possible influencing factors, and detecting pathogens and their antibiotic sensitivi- ties. Multivariate Logistic regression analysis was used to explore the influencing factors. Results There were 65 cases suffered hospital - acquired pneumonia in all 892 stroke patients, with the rate of 7.29%. Pathogen detection showed that the top four pathogens were Acineto- batter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa bacteria and fungus Candida albicans. Logistic regression analysis showed that age, duration of hospitalization, with diabetes, with heart failure, H2 blockers and pre - treated with antibiotics had statistical significance, being independent risk factors of hospital - acquired pneumonia in stroke patients. Conclusion Hospital - acquired pneumo- nia rate in stroke patients stroke was influenced by many factors. In clinical practice, more measures should be taken to reduce the inci- dence of the disease.