高血压病颈动脉粥样硬化斑块发生情况及其干预研究

目的运用高频超声了解高血压患者颈动脉粥样硬化的发生情况并对其进行干预研究。方法对196例原发性高血压患者行颈动脉超声检查,将有斑块者随机分成降压、降压 降脂两组,6个月后复查颈部血管超声。结果(1)高血压合并症越多,斑块检出率越高,斑块严重程度分级越高;(2)6个月后降压 降脂组较单纯降压组颈动脉斑块有明显回退(P<0.05)。结论(1)颈动脉可作为一个良好的体表窗口,反映高血压患者动脉粥样硬化的病变程度。(2)他汀类降脂药对稳定、缩小颈动脉粥样斑块有显著疗效。

The study on incidence and intervention of carotid atherosclerotic plaque in essential hypertension

Objective To investigate the incidence and the intervention effects of carotid atherosclerotic plaque in essential hypertension by color ultrasound.Methods 166 patients with essential hypertension were examined by color ultrasound,and the patients with carotid atherosclerotic plaque were randomly divided into lipid lowing intervention groups and control groups,and re-examined by color ultrasound after 6 months.Results The more the complications of hypertension,the high incidence and critical degree of carotid atherosclerotic plaque were examined.The size of carotid atherosclerotic plaque was reduced significantly after therapy.Conclusion Carotid artery can be a good window to reflect the critical degree of atherosclerosis.Atravatatin is effective in diminishing and stabling carotid atherosclerosis plaques.