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类风湿关节炎患者血清胱抑素C的检测及临床意义
引用本文:蒋耀平,尹智功,肖敬,韦锐斌,李拥军,蒙继勇. 类风湿关节炎患者血清胱抑素C的检测及临床意义[J]. 广西医学, 2011, 33(4): 426-428
作者姓名:蒋耀平  尹智功  肖敬  韦锐斌  李拥军  蒙继勇
作者单位:广西柳州市中医院风湿免疫科,柳州市,545001
摘    要:目的 探讨类风湿关节炎(RA)患者血清胱抑素C(CysC)的变化及临床意义.方法 RA患者45例健康体检者40例(对照组)采用终点散射比浊法测定血清胱抑素C(CysC),采用全自动生化分析仪测定血肌酐(Scr),并计算内生肌酐清除率(Ccr).结果 RA组患者CysC浓度高于对照组,Ccr低于对照组(P均<0.05)....

关 键 词:类风湿关节炎  胱抑素C  肾损害  内生肌酐清除率

Evaluation on the Serum Cystatin C in Patients with Rheumatoid Arthritis and its Clinical Significance
JIANG Yao-pin,YIN Zhi-gong,XIAO Jing,WEI Rui-bin,LI Yong-jun,MENG Ji-yong. Evaluation on the Serum Cystatin C in Patients with Rheumatoid Arthritis and its Clinical Significance[J]. Guangxi Medical Journal, 2011, 33(4): 426-428
Authors:JIANG Yao-pin  YIN Zhi-gong  XIAO Jing  WEI Rui-bin  LI Yong-jun  MENG Ji-yong
Affiliation:(Liuzhou Hospital of Traditional Chinese Medicine,Guangxi,Liuzhou 545001)
Abstract:Objective To investigate the significance of serum cystatin c(CysC)in patients with Rheumatoid Arthritis(RA).Methods The serum levels of CysC were detected by fixed-time nephelometric immunoassay and,and the serum creatinine(Scr)in 40 healthy controls were buy routine biochemistry assay,creatinine clearance(Ccr)was calculated.Results The serum level of CysC in RA was significantly higher than that of healthy group,and the serum level of Ccr was lower than that of healthy group(P0.05).Conclusion The measurement of CysC is helpful in the valuation of patients with RA of early renal damage,there is a rise in blood concentration of CysC in early stage of Rheumatoid Arthritis.
Keywords:Rheumatoid Arthritis  Cystatin C  Renal damage  Creatinine clearance
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