防城港市成年男性非酒精性脂肪肝患病率及其危险因素分析研究

目的 了解一般人群成年男性非酒精性脂肪肝(NAFLD)的患病率,分析其危险因素.方法 以参加防城港市第一人民医院体检的男性人群作为研究对象,内容涉及问卷、一般体格检查、血生化检测及肝脏实时超声检查,筛选出3 238例有完整调查问卷和检查资料的成年男性进行研究.结果 3 238例中检出NAFLD 832例,患病率为25....

Analysis of the Prevalence of Nonalcoholic Fatty Liver Disease and its Risk Factors in a General Adult Males of Fangchenggang City

Objective To investigate the prevalence rate of nonalcoholic fatty liver disease（NAFLD）and its risk factors among adult males in a general population.Methods The large-scale physical examination were conducted for statistical analysis in Fangchenggang First People＇s Hospital.A standard interview,anthropometrics,iochemical studies,and abdominal ultrasonography were required for each participant.Results A total of 3 238 cases of adult men enrolled in the survey,of 832 individuals was diagnosed as NAFLD（25.69%）,while 2 406 healthy subjects were designated as the control group.Among adult males younger than 50 years,the prevalence of NAFLD increased with age,but in participants older than 50 years the case was just the opposite.The mean age,waist circumference,body mass index（BMI）,waist-to-hipratio,contractive pressure,diastolic pressure,fasting plasma glucose（FPG）,total cholesterol（TC）,triglyceride（TG）,low density lipoprotein cholesterol（LDL-C）,ALT,uric acid（UA）,and the presence of overweigh,obesity,hypercholesteremia,hypertriglyceridemia,impairedfasting glucose,diabetes mellitus,hypertension,hyperuricemia,liver dysfunction in NAFLD group was significantly higher than those in control group,but the high density lipoprotein cholesterol（HDL-C）level in NAFLD group was lower than that of control group.Logistic regression showed that TG,BMI,waist circumference,FPG,HDL-C,ALT and UA were highly correlated to NALFD.Conclusion There is a high prevalence of NAFLD among adult males in Fangchenggang.The risk factors for NAFLD are TG,BMI,waist circumference and FPG.HDL-C is the protective factor for NALFD.