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Fatal sepsis in an AIDS patient during therapy for Pneumocystis carinii pneumonia
Authors:Piso R J  Rossi M  Oehler T  Nguyen X M  Täuber M G
Affiliation:(1) Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, CH-8091 Zurich, Switzerland. reinjan.piso@dim.usz.ch, CH;(2) Dept. of Infectious Disease, Inselspital, Bern, Switzerland, CH;(3) Institute for infectious Disease, University of Bern, Switzerland, CH
Abstract:The case of a patient with a newly diagnosed HIV infection and Pneumocystis carinii pneumonia is presented. Despite treatment with high-dose trimethoprim/sulfamethoxazole (TMP/SMX) and prednisone with initial improvement, the patient acutely deteriorated with severe acidosis and died on the 4th day of hospitalization. Cryptococcus neoformans grew the next day in broncheoalveolar lavage (BAL) and blood culture. As simultaneous presence of more than one opportunistic infection can occur in these patients, systematic workup for other common opportunistic infections must be performed. Received: October 12, 2000 · Revision accepted: December 8, 2001 R. J. Piso (corresponding author)
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