| 头孢匹林钠的合成研究 |
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| 引用本文： | 黄金龙,赵经伟,丰理象,任凤英,游莉. 头孢匹林钠的合成研究[J]. 中国抗生素杂志, 2012, 37(6): 455-458 |
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| 作者姓名： | 黄金龙 赵经伟 丰理象 任凤英 游莉 |
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| 作者单位： | 1. 浙江尖峰药业有限公司,金华,321000
2. 中国医药集团总公司四川抗菌素工业研究所,成都,610061 |
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| 摘 要： | 以7-ACA为原料,三步反应合成头孢匹林钠,该反应条件温和,操作方便,收率高,产物结构经元素分析、NMR和MS得到了确证。
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| 关 键 词： | 7-ACA 头孢匹林钠 合成 |
Study on the synthesis of cephapirin sodium |
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| Huang Jin-long , Zhao Jing-wei , Feng Li-xiang , Ren Feng-ying , You Li. Study on the synthesis of cephapirin sodium[J]. Chinese Journal of Antibiotics, 2012, 37(6): 455-458 |
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| Authors: | Huang Jin-long Zhao Jing-wei Feng Li-xiang Ren Feng-ying You Li |
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| Affiliation: | 1 Zhejiang Jianfeng Pharmaceutical Co.,Ltd,Jinhua 32100;2 China Pharmaceutical Group Co., Ltd.,Sichuan Industrial Institute of antibiotics Chengdu 610061) |
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| Abstract: | The cephapirin sodium was synthesized by using 7-Aminocephalosporanic acid as the initial materials.The reaction was readily performed with good yield under mild conditions and convenient operations,The structure was characterized by NMR and MS spectrum. |
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| Keywords: | 7-aminocephalosporanic acid Cephapirin sodium Synthesis |
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