1 313例早产儿眼底疾病筛查结果及分析

目的 分析早产儿眼底疾病的患病率及患早产儿视网膜病变的高危因素,为临床诊治提供参考依据。方法 采用RetCam 3小儿视网膜成像系统对2015年3月-2016年3月出生的所有早产儿进行眼底疾病筛查,并结合患儿的一般临床资料对早产儿视网膜病变进行高危因素分析。结果 对1 313例早产儿进行筛查,一共筛查出301例眼底疾病患儿,其中早产儿视网膜病变208例,非特异性视网膜渗出性病变53例,视网膜出血33例,原始玻璃体动脉残留4例,视神经发育不全1例,永存原始玻璃体增生症1例,黄斑色素沉着1例。Logistic回归分析早产儿视网膜病变的高危因素有低胎龄、低出生体重、不规范吸氧史、多胎及输血史。结论 RetCam 3眼病筛查能在早产儿人群中筛查出眼底疾病;早产儿视网膜病变的高危因素有低胎龄、低出生体重、不规范吸氧史、多胎及输血史。

Screening results and analysis of fundus examination in 1 313 premature infants.

Objective To investigate the incidence of the premature infants and analyse the high risk factors associated with the development of retinopathy of prematurity (ROP) in premature infants. Method Retinal imagine system (RetCam 3) was applied to a screening of the fundus diseases in premature infants born between March 2015 and March 2016,and logistic regress analysis of ROP risk factors was conducted. Results A total of 301 infants with fundus diseases were screened out,consisting of 208 cases of ROP,53 cases of nonspecific exudative retinal lesions,33 cases of retinal hemorrhage,4 cases of original residual vitreous artery,1 case of optic nerve hypoplasia,1 case of persistent hyperplastic primary vitreous and 1 case of macular pigmentation.Logistic regress analysis indicated that young gestational age,low birth body weight,non-standard history of using oxygen,simple polyembryony and transfusion history were high risks for the development of ROP in premature infants. Conclusions RetCam 3 is an important means of fundus examination in premature infants.Young gestational age,low birth body weight,non-standard history of using oxygen,simple polyembryony and transfusion history are high risks for the development of ROP in premature infants.