注意缺陷多动障碍儿童的社会功能与血液微量元素相关性分析

目的 分析注意缺陷多动障碍(ADHD)儿童的血液微量元素与社会功能的相关性,从营养学角度为改善ADHD患儿的社会功能缺陷提供科学依据。方法 应用Weiss's功能性缺陷程度评定量表(WFIRS-P)对144名ADHD儿童社会功能进行评价,检测血液铜、锌、钙、镁、铁、磷、铅的浓度,并计算铜/锌比值,然后对WFIRS-P量表评分与各微量元素水平进行相关的统计学分析。结果 经t检验分析,ADHD患儿血清锌离子(P＜0.05)、镁离子(P＜0.01)明显低于正常对照组,两组间的其余各元素及铜/锌比值差异均无统计学意义(P>0.05)。经多元线性逐步回归分析,发现血清铁的浓度变化与患儿的冒险活动具有相关性(P＜0.05),其余元素与ADHD儿童的家庭、学习和学校、生活技能、自我观念、社会活动等社会功能之间未发现显著的相关性。结论 锌、镁元素可能是ADHD儿童的保护因子,铁元素对ADHD儿童的冒险活动具有影响,微量元素的失衡将对ADHD儿童的社会功能造成损害。

Correlation analysis about attention deficit hyperactivity disorder children's social function and microelement of blood.

Objective To analyse the correlation between blood microelement and the social function of ADHD children,and provide a scientific evidence for ameliorating the social functional of attention dificit hyperactivity disorder (ADHD) children by nutrition. Methods The social function of 144 ADHD children were evaluated by Weiss Functional Impairment Scale-Parent form(WFIRS-P).The levels of microelement including copper,zinc,calcium,magnesium,iron,phosphorus and lead in blood were checked,and calculated the copper/zinc ratio too.Then the correlation of WFIRS-P scores and microelement level was analysed by statistical methods. Results Through the statistical results by t-test,we found the levels of serum zinc (P<0.05) and magnesium (P<0.01) in ADHD children were significantly lower than those in the normal control group,but the others between the two groups and copper/zinc ratio had no significant differences.By the multiple linear stepwise regression analysis,we found that the concentration changes of serum iron associated with ADHD children's risky activities (P<0.05).And the other elements had no significant correlation between social function including family,learning and school,life skills,self-concept and social activities in ADHD children. Conclusion s Zinc,magnesium may be the protection factors of ADHD children.Iron has influence on the risky activities of ADHD children.Imbalance of microelement will cause damage to the social function of ADHD children.