| 国产与进口替考拉宁对224株肠球菌的体外抑菌活性比较研究 |
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| 引用本文： | 李仲兴,王秀华,杨敬芳,时东彦,李继红,陈晶波.国产与进口替考拉宁对224株肠球菌的体外抑菌活性比较研究[J].中国药房,2005,16(8):581-583. |
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| 作者姓名： | 李仲兴 王秀华 杨敬芳 时东彦 李继红 陈晶波 |
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| 作者单位： | 河北医科大学附属第二医院,石家庄市,050000 |
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| 摘 要： | 目的:研究国产替考拉宁对224株肠球菌的体外抑菌活性。方法:采用琼脂稀释法测定国产替考拉宁对169株粪肠球菌和51株屎肠球菌等的最低抑菌浓度(MIC) ,并与进口替考拉宁及其它抗生素进行抑菌效果比较。结果:国产替考拉宁对169株粪肠球菌和51株屎肠球菌的MIC50 分别为0. 125、0 .25μg/ml,MIC90 分别为2、1μg/ml;进口替考拉宁对粪肠球菌和屎肠球菌的MIC50分别为0 .25、0. 25μg/ml,MIC90 分别为1、0 .5μg/ml。结论:两种替考拉宁对224株肠球菌均具有较强的抑菌活性;224株肠球菌对两种替考拉宁的敏感率均为100 %。
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| 关 键 词： | 替考拉宁 肠球菌 抑菌活性 |
| 文章编号： | 1001-0408(2005)08-0581-03 |
| 修稿时间： | 2004年7月16日 |
Comparative Study on the Vitro Antibacterial Activity of Domestic and Imported Teicoplanin against 224 Strains of Enterococci |
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| LI Zhongxing,WANG Xiuhua,YANG Jingfang,SHI Dongyan,LI Jihong,CHEN Jingbo.Comparative Study on the Vitro Antibacterial Activity of Domestic and Imported Teicoplanin against 224 Strains of Enterococci[J].China Pharmacy,2005,16(8):581-583. |
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| Authors: | LI Zhongxing WANG Xiuhua YANG Jingfang SHI Dongyan LI Jihong CHEN Jingbo |
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| Abstract: | OBJECTIVE:To study the vitro antibacterial activity of domestic teicoplanin against224strains of enterococ-ci.METHODS:Determination of MIC of domestic teicoplanin against169strains of entercococcus faecalis and51strains of E.faecium was tested by agar dilution method,and its antibiotic effect was compared with that of the imported teicoplanin and other antibiotics.RESULTS:The MIC 50 of domestic teicoplanin against169strains of E.faecalis and51strains of E.faecium were0.125,0.25μg/ml respectively,MIC 90 were2,1μg/ml respectively;The MIC 50 of imported teicoplanin against E.faecalis and E.faecium were0.25,0.25μg/ml respectively,MIC 90 were1,0.5μg/ml respectively.CONCLUSION:Two kinds of te-icoplanin have strong antibacterial activity against224strains of enterococci;the sensitivity of224strains of enterococci to both kinds was100%. |
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| Keywords: | Teicoplanin Enterococci Antibacterial activity |
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