| 栓必灵对大鼠肠系膜微循环的影响 |
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| 引用本文： | 邓岩辉,张文杰,卢熠,袁博,孙燕燕. 栓必灵对大鼠肠系膜微循环的影响[J]. 中国药房, 2005, 16(8): 579-580 |
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| 作者姓名： | 邓岩辉 张文杰 卢熠 袁博 孙燕燕 |
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| 作者单位： | 1. 沈阳医学院附属第二医院药剂科,沈阳市,110002
2. 沈阳医学院,沈阳市,110006 |
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| 摘 要： | 目的:研究栓必灵对大鼠肠系膜微循环的影响。方法:大鼠分别舌静脉注射栓必灵45、90、180IU/kg ,采用显微录像静画步进法观察给药30min后大鼠肠系膜毛细血管血流速度、血流状态及血管内径的变化。结果:低、中、高剂量组血流速度增加率分别为24.25 %、26. 34 %和25. 88 % ;细动脉内径增加率分别为21. 37 %、27 .13 %和28. 80 % ;细静脉内径增加率分别为6 .70 %、9. 31 %和12 .95 % ;血流状态明显改善。结论:栓必灵有改善大鼠肠系膜微循环的作用。
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| 关 键 词： | 栓必灵 肠系膜 微循环 |
| 文章编号： | 1001-0408(2005)08-0579-02 |
| 修稿时间： | 2004-06-17 |
Effects of Shuanbiling on Mesenteric Microcirculation in Rat |
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| DENG Yanhui,ZHANG Wenjie,LU Yi,YUAN Bo,SUN Yanyan. Effects of Shuanbiling on Mesenteric Microcirculation in Rat[J]. China Pharmacy, 2005, 16(8): 579-580 |
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| Authors: | DENG Yanhui ZHANG Wenjie LU Yi YUAN Bo SUN Yanyan |
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| Abstract: | OBJECTIVE:To study the effects of shuanbiling on mesenteric microcirculation in rat.METHODS:Changes of blood flow velocity,blood flow states and blood vessel diameter of mesentery were observed by microvideo frame to frame30minutes after iv of shuanbiling45,90,180IU/kg respectly.RESULTS:Low,mid,high doses of shuanbiling groups significantly increased the blood flow velocity,which increased by24.25%,26.34%,and25.88%respectively in;The blood vessel diame-ters increased by21.37%,27.13%,and28.80%respectively for arterioles;and6.70%,9.31%,12.95%for venules.Blood flow states were also improved significantly.CONCLUSION:Shuanbiling could improve the mesenteric microcirculation in rat. |
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| Keywords: | Shuanbiling Mesentery Microcirculation |
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