女性高危急性冠脉综合征早期PCI预后分析

目的:探讨女性高危急性冠脉综合征(ACS)患者早期经皮冠状动脉介入治疗(PCI)的预后是否与男性有差别。方法:分析24 h内接受PCI治疗的79例女性高危ACS患者冠脉病变及干预情况,记录手术成功率及随访期间终点事件发生率,并与同期133例男性患者作对照。结果:女性患者平均年龄较男性为高(P<0.01),较少吸烟(P<0．01),较多合并糖尿病(P<0．05)和高脂血症(P<0．05),三支病变较少(P<0．05),而手术成功率及(25．3±8．1)个月心血管事件发生率与男性组无统计学差异(P>0.05)。结论:早期PCI治疗高危ACS其院内疗效与长期预后无性别差异。

Prognosis of High Risk Acute Coronary Syndromes Undergoing Early Percutaneous Coronary Intervention in Females

Objective:To evaluate the influence of sex on the prognosis of high risk acute coronary syndromes treated early with percutaneous coronary intervention(PCI) .Methods: 212 consecutive patients (79 female, 133 male) underwent PCI within the first 24 hours of a high risk acute coronary syndrome.Results: The females were older than the males(71.33 vs 65.35 years, P < 0.01), smoked less (Ovs 29.32%, P < 0.01) and had a higher prevalence of both diabetes (37.97% vs 24.06%, P < 0.05) and hypercholesterolemia(40.50% vs 26.32% , P < 0.05) . The females underwent similar target vessel revascularisation in spite of a lower frequency of three vessel disease compared to the males(13.92% vs 29.32%, F<0.05) . The procedural success rate was comparable (94.947% vs 95.49% ,P > 0.05), and the rate of major cardiac events during hospitalization (5.06% vs 4.51% ,P > 0.05) and long - term follow - up (18.99% vs 12.78%, P > 0.05)remained identical in both sexes,but the females had a greater incidence of access site hematoma(7.59% vs 1.50%,P <0.05) .Conclusion: The progression both in hospital and at 25.3 months with a strategy of early PCI for high risk acute coronary syndromes was comparable in females and males.