| 连续性血液净化对急性呼吸窘迫综合征患者的疗效分析 |
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| 引用本文： | 张新莉,刚丽,蒋志宏.连续性血液净化对急性呼吸窘迫综合征患者的疗效分析[J].中国误诊学杂志,2011,11(7):1513-1514. |
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| 作者姓名： | 张新莉 刚丽 蒋志宏 |
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| 作者单位： | 大连大学附属中山医院急诊医学科,辽宁,大连,116011 |
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| 摘 要： | 目的观察连续性血液净化对急性呼吸窘迫综合征(ARDS)的临床疗效及对血浆炎症介质水平的影响。方法将40例ARDS患者分为2组。观察治疗前后APACHEII评分、动脉血气分析、TNF-α、IL-1β的变化。结果治疗组APACHEII评分、动脉血气分析的改善明显优于对照组,且TNF-α和IL-1β表达较对照组降低。差异有统计学意义(P<0.05)。结论连续性血液净化能有效地清除ARDS患者体内的炎症因子,因而更有利于其呼吸功能的改善。
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| 关 键 词： | 血液滤过 呼吸窘迫综合征 成人/治疗 炎症介导素类/血液 |
Analysis of continuous blood purification on acute respiratory distress syndrome |
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| ZHANG Xin-li,GANG Li,JIANG Zhi-hong.Analysis of continuous blood purification on acute respiratory distress syndrome[J].Chinese Journal of Misdiagnostics,2011,11(7):1513-1514. |
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| Authors: | ZHANG Xin-li GANG Li JIANG Zhi-hong |
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| Institution: | ZHANG Xin-li,GANG Li,JIANG Zhi-hong Department of Emergency,Affiliated Zhongshan Hospital of Dalian University,Dalian 116011,China |
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| Abstract: | Objective To observe the therapeutic effect of continuous blood purification on patients with acute respiratory distress syndrome（ARDS）,and to evaluate the influence on plasma level of inflammatory mediators.Methods 40 patients with ARDS were divided into two groups.APACHE II score,arterial blood gas analysis,plasma levels of TNF-α and IL-1β were measured before and after CBP.Result The improvement of APACHE II score and arterial blood gas analysis in treated group were obviously superior than in control group.TNF-α and IL-1βwere lower in treated group than in control group.The difference was significant（P0.05）.Conclusion CBP can benefit the removal of TNF-α and IL-1β from the body,thus benefiting the stability of the respiration in the patients with ARDS. |
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| Keywords: | Hemofiltration Respiratory Distress Syndrome Adult/therapy Inflammation Mediators/blood |
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