| 应用CHEP/BOD方案治疗晚期中、高度恶性非何杰金氏淋巴瘤的疗效观察 |
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| 引用本文： | 周定. 应用CHEP/BOD方案治疗晚期中、高度恶性非何杰金氏淋巴瘤的疗效观察[J]. 癌症, 1991, 0(6) |
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| 作者姓名： | 周定 |
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| 作者单位： | 湖南省肿瘤医院内科 长沙 |
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| 摘 要： | 本文报告应用CTX,ADM,VP—16,prednisone,BLM—A5,VCR,Dxame—thesone(CHEP/BOD)治疗23例Ⅲ、Ⅳ期中、高度恶性非何杰金氏淋巴瘤。所有病例均经病理学证实。按“工作规范”分类,中度恶性10例,高度恶性13例。全组共用119个疗程,平均每例用5.2个疗程。治疗结果:全组总缓解率87％。CR率78.3％。15例初治病例的CR率93.3％,8例复治病例的CR率50％。达CR的18例中,4例在2年内复发。主要毒副反应为消化道反应、白细胞降低及脱发。无致死性毒副反应发生。
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| 关 键 词： | 非何杰金淋巴瘤 联合化疗 |
CHEP/BOD TREATMENT OF STAGE III AND IV INTERMEDIATE OR HIGH GRADE MALIGNANCY NON-HODGKIN''''S LYMPHOMA |
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| ZHOU Ding. CHEP/BOD TREATMENT OF STAGE III AND IV INTERMEDIATE OR HIGH GRADE MALIGNANCY NON-HODGKIN''''S LYMPHOMA[J]. Chinese journal of cancer, 1991, 0(6) |
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| Authors: | ZHOU Ding |
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| Abstract: | 23 cases of stage III and IV intermediate or high grade non-Hodgkin lymphoma, all histologically proved, were treated with a combination of CTX, ADM, VP-16, Prednisone, BLM-A5, VCR, Dexamethasone(CHEP/BOD). 10 cases were intermediate grade, 13 cases were high grade non-Hodhkin's lymphoma accorling to the working formulation.Results showed that for the whole group, total response rate was 87% and CR rate was 78.3% . For 15 previously untreated ecases, CR rate was 93.3% . For 8 previously treat treated cases, CR rate was 50% . Side effects includen leucopenia and alopecia, no fatal toxecity was encountered. |
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| Keywords: | Non-Hodgkin Lymphoma Combination Chemotherapy |
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