Activated human Hageman factor (XII). |
| |
| Authors: | R J Speer H Ridgway J M Hill |
| |
| Affiliation: | J. K. and Susie L. Wadley Research Institute, Dallas, USA. |
| |
| Abstract: | An improved method for the isolation of highly purified active human Hageman factor has been described. An overall recovery of 25% with a purification of 10(6) has been achieved. Certain of the physical and chemical characteristics of XII have been elucidated. Selective chemical modification of functional groups and a variety of enzymatic assays have been employed in an effort to shed light on the mechanism of action of this procoagulant. |
| |
| Keywords: | |
|
