1. Department of Neurology, The Johns Hopkins Hospital, Baltimore, Md. U.S.A.;2. Department of Pediatric Hematology, The Johns Hopkins Hospital, Baltimore, Md. U.S.A.
Abstract:
Six children with clinical and pathological features of Batten-Vogt syndrome showed autofluorescent material in bone marrow cells and in 5 of them sea-blue histiocytes were seen. It is suggested that bone marrow examination for sea-blue histiocytes and autofluorescenceis a useful screening test for ceroid-lipofuscinosis.