鼻窦灌注液中加用布地奈德在慢性鼻炎鼻窦炎内镜术后治疗效果观察

目的：研究鼻窦灌注液中加用布地奈德在慢性鼻炎鼻窦炎内镜术后的疗效。方法：选择鼻炎鼻窦炎患者110例,随机分为给予鼻窦灌注液冲洗的对照组和在鼻窦灌注液中加用布地奈德冲洗的观察组,每组55例。观察糖精清除时间、呼吸功能以及炎症因子水平。结果：观察组的糖精清除时间、步行后心率、呼吸频率、呼吸困难严重程度分级标准（MRC评分）以及检测炎症因子IL1、IL2、IL4、IL6、IL8水平均低于对照组;1 s呼吸频率、6 min步行距离均明显高于对照组。结论：鼻窦灌注液中加用布地奈德能够有效的改善治疗效果、缓解炎症状态,具有积极的临床价值。

Research on the effect of sinuses perfusate plus budesonide in chronic rhinitis and sinusitis after endoscopic surgery

Objective： To study the effect of sinuses perfusate plus budesonide in chronic rhinitis and sinusitis after endoscopic surgery. Methods： Rhinitis and sinusitis patients were randomly divided into ffect of sinuses perfusate plus budesonide in chronic rhinitis and sinusitis after endoscopic surgery given sinuses perfusate and observation group given sinuses perfusate plus budesonide. Then saccharin clearance time, pulmonary function and inflammatory factor level were observed. Results： saccharin clearance time, heart rate, respiratory rate after walking, MRC score and IL1, IL2, IL4, IL6, IL8 levels of observation group were lower than control group; a second rate, 6 MWT were significantly higher than control group. Conclusion： Sinuses perfusate plus budesonide has positive clinical value for it can improve treatment effect and alleviate inflammatory state.