慢性肺心病并发多器官衰竭（附70例报告）

１９８６～１９９２年我院共收治急性发作期慢性肺心病１９６例，其中因严重肺部感染发生多器官衰竭（ＭＯＦ）者７０例（３５．７％），平均受损脏器２．５个，死亡２６例，总病死率为３７．１％。其中２和３个脏器受损者的病死率分别为２０．１％和４４．４％，而４和５个脏器受损者则均死亡。血气分析显示ｐＨ和ＰａＯ２值与受损脏器数目呈负相关，而ＰａＣＯ２值与受损脏器数目呈正相关。本文讨论了肺心病因肺部感染并发ＭＯＦ的发病机理，并提出防治的措施。

Chronic Cor Pulmonale Complicated by Multiple Organ Failure(A 70 Cases Report)

cases of chronic cor puolmonale in acute bout were treated in our hospital from 1986 to 1992 and multiple organ failure(MOF) occurred in 70 of these Patients(35.7%) due to severe pulmonary infection. The average organ involvement of 2.5 and the total fatality rate of 37.14%(26/70) were observed in these 70 Patients. The fatality rate was 20.09% and 44.44% respectively in patients with 2 and 3 organs involved and 100% in those with 4 and 5 organs were affected. The pH and PaO2 values were markedly negatively correlated(P<0.01), while the PaCO2 value was highly positive correlated(P<0.01) to the injuried organ number, as shown by a blood gas analysis. The mechanism regarding cor pulmonale complicated with MOF was discussed and the preventive and therapeutic measures about MOF were put forward in this paper.