| 99Tcm-甲氧基异丁基异腈双时相平面显像和SPECT/CT断层显像诊断原发性甲状旁腺功能亢进症 |
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| 引用本文： | 张祥铭,张敏,胡佳佳,席云,孙晨玮,李彪.99Tcm-甲氧基异丁基异腈双时相平面显像和SPECT/CT断层显像诊断原发性甲状旁腺功能亢进症[J].中国医学影像技术,2014,30(6):850-853. |
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| 作者姓名： | 张祥铭 张敏 胡佳佳 席云 孙晨玮 李彪 |
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| 作者单位： | 上海交通大学医学院附属瑞金医院核医学科, 上海 200025;上海交通大学医学院附属瑞金医院核医学科, 上海 200025;上海交通大学医学院附属瑞金医院核医学科, 上海 200025;上海交通大学医学院附属瑞金医院核医学科, 上海 200025;上海交通大学医学院附属瑞金医院核医学科, 上海 200025;上海交通大学医学院附属瑞金医院核医学科, 上海 200025 |
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| 基金项目： | 国家临床重点专科建设项目。 |
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| 摘 要： | 目的 观察99Tcm-甲氧基异丁基异腈（99Tcm-MIBI）双时相平面显像和SPECT/CT断层显像诊断原发性甲状旁腺功能亢进症（PHPT）的价值。方法 收集术前接受99Tcm-MIBI双时相平面显像和SPECT/CT断层显像的疑似PHPT患者40例，所有患者均接受手术治疗。以术后病理诊断为金标准，计算并比较99Tcm-MIBI双时相平面显像和SPECT/CT断层显像诊断PHPT的灵敏度。结果 40例中，38例经病理确诊为PHPT，99Tcm-MIBI双时相平面显像灵敏度为89.47%（34/38），99Tcm-MIBI SPECT/CT断层显像灵敏度为94.74%（36/38），差异无统计学意义（P>0.05）。对不同病灶大小及不同甲状旁腺素水平PHPT，99Tcm-MIBI双时相平面显像与SPECT/CT断层显像诊断灵敏度差异均无统计学意义（P均>0.05）。结论 99Tcm-MIBI双时相平面显像和SPECT/CT断层显像诊断PHPT灵敏度高。
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| 关 键 词： | 甲状旁腺功能亢进 原发性 99m 锝甲氧基异丁基异腈 体层摄影术 发射型计算机 单光子 |
| 收稿时间： | 2014/3/14 0:00:00 |
| 修稿时间： | 2014/4/24 0:00:00 |
99Tcm-methoxyisobutylisonitrile dual-phase planar and SPECT/CT scanning in diagnosis of primary hyperparathyroidism |
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| ZHANG Xiang-ming,ZHANG Min,HU Jia-ji,XI Yun,SUN Chen-wei and LI Biao.99Tcm-methoxyisobutylisonitrile dual-phase planar and SPECT/CT scanning in diagnosis of primary hyperparathyroidism[J].Chinese Journal of Medical Imaging Technology,2014,30(6):850-853. |
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| Authors: | ZHANG Xiang-ming ZHANG Min HU Jia-ji XI Yun SUN Chen-wei and LI Biao |
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| Institution: | Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China |
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| Abstract: | Objective To observe the value of 99Tcm-methoxyisobutylisonitrile (99Tcm-MIBI) dual-phase planar and SPECT/CT scanning in diagnosis of primary hyperparathyroidism (PHPT). Methods Forty patients of suspected PHPT who underwent preoperative 99Tcm-MIBI dual-phase planar and SPECT/CT scanning and surgical operation were collected. The sensitivity of 99Tcm-MIBI dual-phase planar and SPECT/CT scanning was calculated and compared taken pathological results as gold standard. Results Thirty-eight patients were diagnosed as PHPT, and the sensitivity of 99Tcm-MIBI dual-phase planar scanning and 99Tcm-MIBI SPECT/CT scanning in diagnosing PHPT was 89.47% (34/38) and 94.74% (36/38), respectively (P>0.05). In addition, for PHPTs with different size of abnormal parathyroid and different level of parathyroid hormone, there as no statistical difference of sensitivity between 99Tcm-MIBI dual-phase planar and SPECT/CT scanning. Conclusion Both 99Tcm-MIBI dual-phase planar scanning and 99Tcm-MIBI SPECT/CT scanning have high sensitivity in diagnosing PHPT. |
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| Keywords: | Hyperparathyroidism primary Technetium Tc 99m sestamibi Tomography emission-computed single-photon |
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