Echocardiographic evaluation of systolic and diastolic function in patients with cardiac amyloidosis |
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| Authors: | Liu Dan Niemann Markus Hu Kai Herrmann Sebastian Störk Stefan Knop Stefan Ertl Georg Weidemann Frank |
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| Institution: | aDepartment of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany;bDepartment of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany;cComprehensive Heart Failure Center, University of Würzburg, Würzburg, Germany |
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| Abstract: | The typical appearance of cardiac amyloidosis using standard echocardiographic techniques is usually a late finding only in patients with relatively advanced stages of the disease. Early noninvasive identification of cardiac amyloidosis is of growing clinical importance. Newer echocardiographic techniques, including tissue Doppler imaging and deformation imaging (strain rate imaging and 2-dimensional speckle tracking), are powerful tools for quantifying regional myocardial motion and deformation. Using these advanced techniques, early functional impairment in cardiac amyloidosis may be detectable when the results of standard echocardiography are still normal or inconclusive. This review provides a comprehensive overview of the different echocardiographic approaches for the assessment of systolic and diastolic function in patients with cardiac amyloidosis. Special attention is paid to regional myocardial function assessed by tissue Doppler imaging, strain rate imaging, and 2-dimensional speckle-tracking imaging. |
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