孕期监测宫颈长度与先兆早产的相关性

目的：探讨孕期监测宫颈长度与先兆早产的相关性，预测孕妇发生早产的临床价值，为今后临床诊治提供参考和借鉴。方法本研究随机选取我院2012年10月～2013年10月期间收治的无任何合并症及并发症孕妇177例，孕期内行常规超声监测宫颈长度，按分娩时间分为两组：先兆早产（A）组138例，早产（B）组39例，分析孕期监测宫颈长度与先兆早产的相关性。结果A组平均宫颈长度为（3.29±0.62）cm明显长于B组的（2.67±0.64）cm，差异有统计学意义（t=3.5083，P=0.0132）；宫颈长度改变是孕妇先兆早产的主要特征。以宫颈长度3.0cm为界，宫颈长度预测孕妇发生早产的敏感度为92.31%（36/39），特异度为93.47%（129/138），阳性预测值为80.00%（36/45），阴性预测值为97.73%（129/132）。结论宫颈长度改变是孕妇先兆早产的主要特征，对宫颈长度＜3.0cm的孕妇应高度警惕其发生早产，对于宫颈长度＞3.0cm的孕妇，应根据其具体的临床表现对症用药，保证母婴安全。采用超声监测孕期宫颈长度能客观、准确地预测早产，是一种安全、有效、可靠的监测方法，值得在临床实践中广泛的应用和推广。

Correlation between pregnancy monitoring of cervical length and threatened premature labor

Objective To investigate the correlation between pregnancy monitoring of cervical length and threatened premature labor and the clinical value of predicting premature labor in order to provide reference for future clinical diagnosis and treatment. Methods 177 pregnant women without complications or combinations admitted to our hospital from October 2012 to October 2013 were selected to receive the conventional ultrasound monitoring of cervical length during pregnancy and divided into two groups according to the labor time：the threatened premature labor group（A） with 138 patients and the premature labor group（B） with 39 patients.The correlation between pregnancy monitoring of cervical length and threatened premature labor was analyzed. Results The average cervical length of group A was（3.29±0.62）cm,which was significantly longer than the（2.67±0.64）cm of group B（t=3.5083,P=0.0132）,with statistically significant difference. The change of cervical length was the main feature of threatened premature labor in pregnant women. With 3.0 cm as the boundary of cervical length, the sensitivity of cervical length in predicting premature labor was 92.31%（36/39）,the specificity was 93.47%（129/138）,the positive predictive value was 80.00%（36/45）,and the negative predictive value was 97.73%（129/132）. Conclusion The change of cervical length is the main feature of threatened premature labor in pregnant women.For pregnant women with cervical length 〈 3.0cm,high attention should be paid to avoid premature labor. For pregnant women with cervical length 〉 3.0cm,medication should be conducted based on the specific clinical manifestations to ensure maternal and child safety.The application of ultrasound monitoring of cervical length can predict premature labor objectively and accurately,thus is a safe, effective and reliable monitoring method and worthy of wide application and promotion in clinical practice.