老年慢性心力衰竭合并低钠血症临床防治82例回顾性分析

目的：探讨老年慢性心力衰竭合并低钠血症的临床防治。方法2012年1月～2014年2月期间我院诊治的82例老年慢性心力衰竭合并低钠血症患者，作为观察组研究对象，另选同期82例老年慢性心力衰竭但不合并低钠血症患者，作为对照组研究对象，观察和比较两组病死率、住院时间、LVEF。将82例老年慢性心力衰竭合并低钠血症患者随机分为A组（常规抗心衰）和B组（常规抗心衰基础上，纠正低钠血症），对两组治疗后血钠水平、临床疗效，进行观察和比较。结果与对照组相比，观察组病死率（29.3% vs 11.0%）、住院时间（15.0±3.0）d vs（10.5±2.5）d明显升高，LVEF明显减少（36.5±0.1）%vs（43.7±0.1）%， P＜0.05；与A组相比，B组治疗后血钠水平（136.7±3.4）mmol/L vs（129.0±2.9）mmol/L及总有效率（73.2%vs 43.9%）明显提高，P＜0.05。结论对于老年慢性心力衰竭合并低钠血症患者，应在抗心衰治疗基础上，积极纠正低钠血症，改善患者的心功能及预后质量。

The retrospective analysis of the clinical prevention and treatment about 82 elderly patients with chronic heart failure combined with hyponatremia

Objective To study the clinical prevention and treatment about the elderly patients with chronic heart failure combined with hyponatremia. Methods The 82 elderly patients with chronic heart failure combined with hyponatremia in our hospital during the period from Jan 2012 to Feb 2014 were regarded as the subjects of the observation group, and the 82 patients with chronic heart failure without hyponatremia in the same period were regarded as the subjects of the control group. The fatality rate, hospitalization time, and LVEF in the two groups were observed and compared. The 82 elderly patients with chronic heart failure combined with hyponatremia were randomized into the A group（routine anti-heart failure） and the B group（based on the routine anti-heart failure, addition to the correction of hyponatremia）. The blood sodium levels after the treatment and the clinical efficacy in the two groups were observed and compared. Results Compared with the control group, the fatality rate（29.3% vs 11.0%）and hospitalization time（15.0±3.0）d vs（10.5±2.5）d were significantly increased and the LVEF levels （36.5±0.1）%vs（43.7±0.1）%were obviously decreased in the observation group（P〈0.05）;compared with the A group, the blood sodium levels（136.7±3.4）mmol/L vs（129.0±2.9）mmol/L and the total effective rate（73.2%vs 43.9%）were significantly increased after treatment in the B group（P〈0.05）. Conclusion For the elderly patients with chronic heart failure combined with hyponatremia, the positive correction of hyponatremia based on the routine anti-heart failure treatment should done and then can improve the patients＇ cardiac function and prognosis quality.