高脂血症性急性胰腺炎的临床特征分析

目的：分析高脂血症性急性胰腺炎的临床特征。方法选取2009年2月～2014年3月在我院进行治疗的急性胰腺炎患者84例，分为高脂血症性急性胰腺炎组（25例）和胆源性急性胰腺炎合并高脂血症组（59例），对高脂血症性急性胰腺炎组和胆源性急性胰腺炎合并高脂血症组患者的临床一般特征、临床实验室相关指标和临床并发症进行比较分析。结果高脂血症性急性胰腺炎组的男性比例低于胆源性急性胰腺炎合并高脂血症组，而年龄、Ranson评分、SAP人数、APACHE-Ⅱ评分及CT评分均显著低于胆源性急性胰腺炎合并高脂血症组（P＜0.05）；胆源性急性胰腺炎合并高脂血症的血尿淀粉酶、甘油三酯、总胆固醇、谷丙转氨酶、谷草转氨酶、总胆红素和直接胆红素均显著高于单纯性高脂血症性急性胰腺炎，血钙低于单纯性高脂血症性急性胰腺炎（P＜0.05）。胆源性急性胰腺炎合并高脂血症组的胰腺假性囊肿的发生率、胸腔积液的发生率、肺部感染发生率、住院天数、复发率和死亡率均显著高于高脂血症性急性胰腺炎组。结论高脂血症作为急性胰腺炎中较为常见的病因，需要与其他类型的急性胰腺炎进行鉴别，临床诊治应更具针对性。

The clinical analysis of clinical characteristic of hyperlipidemia acute pancreatitis

Objective To analyze the clinical characteristic of hyperlipidemia acute pancreatitis. Methods 84 acute pancreatitis patients in our hospital from February 2009 to March 2014 were selected for this study,the patients were divided into two groups according to the diagnostic criteria.The groups were hyperlipidemia acute pancreatitis and acute biliary pancreatitis combined with hyperlipidemia respectively, then the general characteristic,index of clinical examination and complication were observed and analyzed. Results The number of men in group hyperlipidemia acute pancreatitis was lower than group of acute biliary pancreatitis combined with hyperlipidemia,the age,Ranson score,number of SAP,APACHE-Ⅱ score,and CT score were lower than group of acute biliary pancreatitis combined with hyperlipidemia（P〈0.05）;the amylase of blood and urine,triglyceride,total cholesterol,ALT,AST,total bilirubin and direct bilirubin in group of acute biliary pancreatitis combined with hyperlipidemia were higher than group of hyperlipidemia acute pancreatitis,in the meantime,the blood calcium was lower（P 〈 0.05）.Morbidity of pancreatic pseudocysts, morbidity of pleural effusion,morbidity of pulmonary infection,days of hospitalization,the recurrence rate,mortality in goup of acute biliary pancreatitis combined with hyperlipidemia were higher than group of hyperlipidemia acute pancreatitis（P〈0.05）. Conclusion Hyperlipidemia is one of the most common etiology of acute pancreatitis,it should be identified from other etiologies,and be treated with pertinency.